When the Rev War began, he joined the company of SGT Samuel Hay, 6th PA Battalion, enlisting on 12 Feb 1776. He fought at the battle of the Three Rivers, in Canada, and his brother James was killed there. Samuel reenlisted the following year, serving serving with the 7th PA Regiment, one of the units under the command of GEN Anthony Wayne. He fought in the battles of Paoli, Brandywine, and Germantown, and retreated with Washington's army to Valley Forge for the winter of 1777-78. After the war, he married Esther John(s), a Quaker woman from Chambersburg, in 1781 and they migrated to the frontier in western PA where they carved out a farm in Fayette County. They had six sons before Esther died in 1802. Samuel married a second time, to the widow, Agnes McWhirter Robinson, and had one daughter by her. He outlived her as well.